The main plot line develops around school chemistry teacher Walter White, who finds out that he had cancer of the lungs. Given the difficult financial situation of the family, as well as prospects for (Walter's wife, Skyler, is pregnant with her second child, and my son ICP), Walter decides to engage in the manufacture of methamphetamine. For this he draws his former student Jesse Pinkman, once expelled from school, with the active assistance of the White. Pinkman himself engaged in the manufacture of methamphetamine, but the day before in a raid DEA and he lost his partner in crime lab. Walter takes its name Heisenberg, which he later would call his "trademark".
Also in the series play an important role next of kin: Skyler - Walt's wife, Skyler's sister - Marie and her husband Hank. Hank is a DEA is the principal investigator on the "case of Walter" about the loss of inventory from the school chemistry classroom. Further investigation Hank directly associated with the effects of Wight, which makes the story even more tension.